From Executive Producer Paul Attanasio, the creator of Homicide: Life on the Street, comes a new take on mystery, where the villain is a medical malady and the hero is a cantankerous doctor who trusts no one, least of all his patients. DR. Greg House (Hugh Laurie, Life with Judy Garland: Me and My Shadows) is irreverent, controversial, devoid of bedside manner and wouldn't even talk to his patients if he could get away with it, but he is brilliant diagnostician and only the most dire cases come his way. House and his hand-picked team of experts will do whatever it takes – legal or not – to make the diagnoses that will solve these medical mysteries and save lives.